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Arch Biochem Biophys 444(2):139158

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Advances in biomarkers and genomic profiling have enabled personalized approaches, enhancing precision medicine

Increased release of glutamate from presynaptic terminals activates N -methyl-D-aspartate (NMDA) receptors on postsynaptic terminals to lead to a widespread neuronal depolarization or spreading depression, further disrupting the sodium ion, potassium ion, and calcium ion equilibria (Langlois et al., 2006)

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Mercury is a known neurotoxin, but it is important that we put it into context